Alzheimer's Foundation of America

Foundation of America

Alzheimer’s Foundation of America Awards $250,000 Grant to the City College of New York for Alzheimer’s Research Project

(July 20, 2022)—The Alzheimer’s Foundation of America (AFA) has awarded a $250,000 research grant to The City College of New York (CCNY) to fund new Alzheimer’s research which could potentially lead to the development of new medications to treat Alzheimer’s disease. The project aims to learn more about the role that disrupting the amyloid precursor protein (APP) plays in causing Alzheimer’s disease.

“Scientists have been working hard and making progress, but there is still more we need to learn and discover about Alzheimer’s disease,” said AFA Founder and Board Chair Bert E. Brodsky. “We are pleased to support CCNY’s research and are hopeful that it will lead to the breakthrough all of us are hoping and praying for.”

“Every dollar invested in Alzheimer’s research is an investment in hope,” said AFA President & CEO Charles J. Fuschillo, Jr. “CCNY’s research has the potential to unlock some of the mysteries surrounding Alzheimer’s disease and hopefully facilitate new treatments, which would be a game-changer in the fight against Alzheimer’s. AFA is proud to support their efforts.”

The APP gene family is essential for viability in mammals, but its function is unclear. Mutations in the genes for APP and in the enzymes that interact with APP have been found in familial Alzheimer’s disease (a form of Alzheimer’s disease which is linked to genes and affects at least two generations of a family), suggesting that disruption of APP can lead to Alzheimer’s disease.

Led by Christine Li, PhD, Principal Investigator and a Professor with CCNY’s Department of Biology, the project aims to identify the role that APP plays in brain health and Alzheimer’s disease using the C. elegans model system. This research can then be translated into discoveries in mammals that could potentially lead to the development of new medications to treat Alzheimer’s that do not interfere with APP function.

“We are immensely grateful to the Alzheimer’s Foundation of America and its donors for their support of our research,” said Dr. Li. “Alzheimer’s disease is a devastating disease not only to the individual, but to the family. All different avenues of research must be pursued to identify possible therapies to alleviate symptoms and, ultimately, to find a cure.”

“An estimated 6 million Americas are living with Alzheimer’s disease and that number is estimated to almost double within the next few decades. This grant from the Alzheimer’s Foundation of America will support the important research being led by Professor Christine Li and her research team. We are grateful to AFA’s Board Chairman, Bert Brodsky, CCNY class of 1964, Charles Fuschillo, Jr, AFA’s President and CEO and the AFA Board for their support and partnership, which we hope will further the important scientific work being done on our campus and around the world,” said Vice President for Institutional Advancement and Communications Dee Dee Mozeleski, who is also the executive director of The Foundation for City College, Inc.

AFA is able to award research grants such as this through the generosity of individuals and organizations. To make a donation to support AFA’s research efforts, as well as programs and services for families affected by Alzheimer’s disease, visit or call AFA at 866-232-8484.